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Intelligent Software

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Intelligent Software

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Intelligent Software

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Intelligent Software

Advances in data processing, cloud infrastructure, and artificial intelligence allow for a fundamentally new class of application layer software products to be built which bake “intelligence” into all layers of the workflow. 

We believe that this type of machine-assisted and computationally-aided workflow will be the predominant theme in application layer software this decade.

Applying reinforcement learning to fundamentally rethink how fresh food inventory is procured and managed

Applying reinforcement learning to fundamentally rethink how fresh food inventory is procured and managed

Using advances in search, data processing, and large language models to rethink financial research

Using advances in search, data processing, and large language models to rethink financial research

Utilizing WebGPU and Diffusion Models to 100x the iteration loop of graphics designers

Utilizing WebGPU and Diffusion Models to 100x the iteration loop of graphics designers

Utilizing large language models to rethink how drugs are approved

Utilizing large language models to rethink how drugs are approved

AI Copilot for software engineering teams

AI Copilot for software engineering teams

LLM-enabled agent assisting engineering teams with ad-hoc requests

LLM-enabled agent assisting engineering teams with ad-hoc requests

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Areas we’re excited about

Computationally aided design tools

Rethinking the workflow of all knowledge workers designing complex systems (e.g. architects, hardware engineers, video editors, software engineers, accountants).

Data-driven security

Cybersecurity tools that leverage novel sources of data and/or methods of processing data to reduce noise and improve signals.

Next generation data management and search

The ability to capture, collect, structure, and understand information at scale has vastly improved. We see substantial opportunities for vertical applications in various markets, such as business intelligence and observability.

Vertical agents

Building LLM-enabled agentic systems to automate highly specialized workflows or tasks.

Rebuilding legacy tools and services with AI

Many categories traditionally dominated by decades-old software and consulting services, such as systems integrators, outsourced 3D artists, and certain legal and compliance tasks, can now be completely rethought thanks to AI.

Advanced simulation

Tools leveraging breakthroughs in computation to allow for higher fidelity simulation and analysis of complex systems.

Insights

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The new dawn of weather forecasting

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Breakthrough advancements in understanding climate risk: our investment in First Street

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Building modern financial infrastructure for the changing energy sector: Our investment in ElectronX

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All applications are becoming distributed systems

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Building Skylo: Parth Trivedi’s lessons in scaling a global network

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From Series A to Salesforce: Celebrating Own

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Meet Bauplan: making all software engineers data engineers

Bauplan is a new serverless data platform that makes complex data pipelines accessible to all software engineers—not just specialists. Built on Python and object storage, it lets devs build, query, and version data with ease using familiar tools.

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Meet Capsule: making high-quality video accessible to every brand.

Capsule makes high-quality, on-brand video creation scalable across teams. With AI-assisted editing and reusable design systems, it empowers anyone to produce pro-grade video—without agencies. Used by Ramp, HubSpot & more to create 10–100x more content at agency-level quality.

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Case Study: How an RDI process led two entrepreneurs to revolutionize alternatives reporting

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Our investment in Character Bio - deep real-world therapeutic discovery and development

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Embracing biological complexity: our investment in Passkey Therapeutics

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A leap in genomic medicine: why we invested in Exsilio Therapeutics

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AI as the new interface to government

Unlocking the $100B opportunity in B2B2G

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Master and Commander: going from records to results and the System of Action future

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The next industrial unicorn: Where is AI rapidly transforming the physical economy

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